ReoPro (abciximab) is a member of a class of anticoagulant drugs that function by inhibiting the role of platelets in hemostasis. Which of the following protein complexes is the target of ReoPro action?

Question

Quizplus · Accepted Answer

ReoPro (abciximab) targets the GPIIb-GPIIIa complex on platelets, inhibiting platelet aggregation and thrombus formation. Abciximab is a GPIIb-GPIIIa antagonist, which is an anticoagulant drug that inhibits platelet aggregation regardless of the agonist. Therefore, abcixamab more completely inhibits platelet aggregation than does aspirin or clopidogrel.

ReoPro (Abciximab) Is a Member of a Class of Anticoagulant