$\gamma$ $\sigma$ T cells may be important for recognition of common antigens at epithelial boundaries between the host and the external environment.The $\gamma$ $\sigma$T cells differ from the $\alpha$$\beta$ T cells in which one of the following ways?
A)($\gamma$ $\sigma$) T cells recognize only nonprotein antigens.
B)($\gamma$ $\sigma$) T cells are not MHC-restricted and do not recognize MHC-associated antigens.
C)The $\gamma$ $\sigma$ TCR complex contains CD3$\gamma$ or CD3$\sigma$ but not CD3? .
D)Most mature $\gamma$ $\sigma$ T cells express either CD4 or CD8 but not both.
E)($\gamma$ $\sigma$ ) T cells lack key biologic activities,including the ability to lyse target cells.

Question

$\gamma$ $\sigma$ T cells may be important for recognition of common antigens at epithelial boundaries between the host and the external environment.The $\gamma$ $\sigma$T cells differ from the $\alpha$$\beta$ T cells in which one of the following ways?
A)($\gamma$ $\sigma$) T cells recognize only nonprotein antigens.
B)($\gamma$ $\sigma$) T cells are not MHC-restricted and do not recognize MHC-associated antigens.
C)The $\gamma$ $\sigma$ TCR complex contains CD3$\gamma$ or CD3$\sigma$  but not CD3? .
D)Most mature $\gamma$ $\sigma$  T cells express either CD4 or CD8 but not both.
E)($\gamma$ $\sigma$ ) T cells lack key biologic activities,including the ability to lyse target cells.

Quizplus · Accepted Answer

T cells expressing the $\gamma$ $\sigma$ TCR are a lineage distinct from the much more numerous  $\alpha$$\beta$-expressing T lymphocytes.The $\gamma$ $\sigma$  T cells do not recognize MHC-associated peptide antigens and are not MHC restricted.Some $\gamma$ $\sigma$  T cells recognize protein or nonprotein antigens that do not require processing or particular types of antigen-presenting cells for their presentation.The $\gamma$ $\sigma$ heterodimer associates with the same CD3 and $\zeta$proteins as do  $\alpha$$\beta$ receptors.Most $\gamma$ $\sigma$cells do not express CD4 or CD8.The $\gamma$ $\sigma$cells are capable of several biologic activities,including secretion of cytokines and lysis of target cells.

γ\gammaγ σ\sigmaσ T Cells May Be Important for Recognition of Common Antigens

$\gamma$ $\sigma$ T Cells May Be Important for Recognition of Common Antigens