What effect occurs when the binding of epigenetic factors to histone proteins causes DNA to be tightly wound?
A) Genes are less accessible for use in protein synthesis.
B) Genes are more accessible for use in protein synthesis.
C) Genes develop potentially cancer-causing mutations.
D) Genes are better able to defend against cancer-causing chemicals in foods.

Question

Quizplus · Accepted Answer

When DNA is tightly wound, it becomes more difficult for transcription factors and RNA polymerase to access the genes, reducing their accessibility for use in protein synthesis. This can have the effect of decreasing gene expression or even completely silencing certain genes. This can be a result of the binding of epigenetic factors to histone proteins, which change the structure of chromatin and affect the packing of DNA. Tighter winding of DNA is associated with a more condensed chromatin structure, which is typically associated with lower levels of gene expression.

What Effect Occurs When the Binding of Epigenetic Factors to Histone