The conversion of glucose to glucose 6-phosphate is an enzyme-catalyzed reaction.During this reaction, the enzyme hexokinase folds around the substrates to bring reactive side chains from the active site into alignment with the substrates.This change in hexokinase is an example of

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The change in hexokinase that occurs during the glucose to glucose 6-phosphate conversion is an example of induced fit. This refers to the conformational change of an enzyme induced by binding to its substrate(s), which brings reactive side chains into alignment with the substrate(s). This change allows for proper catalysis to occur. Solvent exclusion and hydrophilic interactions do not accurately describe this process, and metal ion exchange is not relevant to this particular reaction.

The Conversion of Glucose to Glucose 6-Phosphate Is an Enzyme-Catalyzed