Enzymes have active sites which have the greatest complementarity to the:
A) substrate.
B) transition state.
C) product.
D) both substrate and product.
E) none of the above.

Question

Quizplus · Accepted Answer

Enzymes catalyze reactions by lowering the activation energy required for the reaction to occur. The active site of an enzyme is specifically shaped to bind to the transition state of the reaction, which is the unstable intermediate state between the substrate and product. By binding to the transition state, the enzyme stabilizes it and lowers the energy required for the reaction to proceed. Therefore, the active site has the greatest complementarity to the transition state, not the substrate or product.

Enzymes Have Active Sites Which Have the Greatest Complementarity to The