The mechanism of chymotrypsin involves which of the following elements?
A) deprotonation of an active site Asp residue by His to start the reaction
B) formation of an acyl-enzyme intermediate that must be hydrolyzed to complete the reaction
C) stabilization of the positively charged His by a Gln residue
D) direct deprotonation of water by His to generate a hydroxide ion for initiation of the reaction
E) both a and b occur

Question

Quizplus · Accepted Answer

Chymotrypsin's mechanism involves the formation of an acyl-enzyme intermediate, which is a key step that must be hydrolyzed to complete the reaction.

The Mechanism of Chymotrypsin Involves Which of the Following Elements