Effective HIV-1 protease inhibitors should have all of the following characteristics EXCEPT:
A) effective delivery in sufficient quantities to the desired site(s) of action in the organism.
B) relative specificity for the HIV-1 protease.
C) a backbone −OH group that forms a weak association with the two active-site carboxyl groups of the protease.
D) results in inhibiting the production of new virus particles in cells of infected patients.
E) broad spectrum enough to be effective against mutant viral forms.

Question

Quizplus · Accepted Answer

The characteristic of having a −OH group that forms a weak association with the two active-site carboxyl groups of the protease is not essential for an effective HIV-1 protease inhibitor.

Effective HIV-1 Protease Inhibitors Should Have All of the Following