If the substrate for an enzyme catalyzed reaction contained a negative charge, which of the following amino acids would most likely be present in the active site to provide electrostatic destabilization of the ES complex?
A) Val
B) Asp
C) Arg
D) Ser
E) Gln

Question

Quizplus · Accepted Answer

Aspartic acid (Asp) is a negatively charged amino acid, so it would provide electrostatic destabilization of the ES complex if the substrate contained a negative charge.

If the Substrate for an Enzyme Catalyzed Reaction Contained a Negative