The LAT:Gads:SLP-76 complex that assembles following TCR stimulation provides the scaffold for initiating multiple downstream signaling modules, leading to actin polymerization, integrin activation, and gene expression.
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Q15: All of the modular protein domains used
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Q17: The TCR and BCR are each composed
Q18: Scaffold proteins are often phosphorylated at multiple
Q19: Diacyl-glycerol (DAG) is one of the
Q21: A mutant B cell line is
Q22: Unlike TCR signaling, B cell receptor (BCR)
Q23: Antigen receptor signaling and lymphocyte activation.antibody
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Q25: Phosphorylation of signaling proteins can have activating
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