Phosphorylation of signaling proteins can have activating or inhibitory effects on protein function. In many cases, such as the activation of mTOR, the phosphorylation of an inhibitory protein leads to inactivation of the inhibitor, resulting in downstream signaling. T-cell receptor signaling leads to enhanced integrin-mediated cell adhesion

Question

Quizplus · Accepted Answer

This statement is true. T-cell receptor signaling can lead to enhanced integrin-mediated cell adhesion, which is important for the activation and movement of T cells.

Phosphorylation of Signaling Proteins Can Have Activating or Inhibitory Effects